UP NEXT: Kyle Chin, Genesis Tissue

Advanced Manufacturing for Personalized Tissue Reconstruction

Monday, December 14, 2026 | 2:00 ET

Abstract: GenesisTissue Inc. is a biotechnology company leveraging Vat Photopolymerization to develop the next generation of personalized surgical solutions for soft-tissue reconstruction, beginning with the breast. Breast cancer is one of the most diagnosed cancers worldwide, affecting more than 2.3 million people globally and approximately 300,000 people in the United States annually. With five-year relative survival rates exceeding 90% in the US, many patients are living beyond diagnosis and treatment. However, breast-conserving surgery (i.e. lumpectomy) and mastectomy can leave tissue defects that negatively affect survivorship as well as pose significant reconstructive challenges. By combining additive manufacturing, biomaterials engineering, and patient-specific design, GenesisTissue aims to make breast reconstruction more predictable while advancing regenerative approaches that support tissue ingrowth and the gradual replacement of scaffold materials with native tissue. This work illustrates broader opportunities and challenges at the intersection of additive manufacturing and regenerative medicine, including scaffold design, degradable and soft material formulation, manufacturing processes, biocompatibility, and characterization.